Bone marrow stem cells contribute to repair of the ischemically injured renal tubule
J. Clin. Invest. Sujata Kale, et al. 112:42 doi:10.1172/JCI17856 [Go to this article.]

Figure 3
Ischemia mobilizes Lin^–Sca-1⁺ cells. Peripheral blood from a mouse 24 hours after sham operation (a) or 25 minutes of unilateral I/R (b) was labeled for detection of Lin⁺ and Sca-1⁺ cells and analyzed on a FACS. Lin^–Sca-1⁺ stem cells were not seen in the circulation of the control animals (a, lower right quadrant); the 1.4% of cells detected is equal to the value seen with the unrelated isotype control antibody and is therefore indistinguishable from background. In contrast, 23.8% of the circulating cells were Lin^–Sca-1⁺ stem cells 24 hours after I/R (b, lower right quadrant).