The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
J. Clin. Invest. Aimin Xu, et al. 112:91 doi:10.1172/JCI17797 [Go to this article.]

Figure 6
Effects of adiponectin on alcohol-induced suppression of hepatic CPT I activity (a) and fatty acid oxidation (b). Three groups of animals were treated with LC diet, LE diet, or LE + Ad diet as described in Figure 4. The activity of CPT I was determined by measuring ³H palmitoylcarnitine formed in digitonin-permeabilized hepatocytes. The rates of fatty acid oxidation were analyzed by monitoring nanomoles of [1-¹⁴C]palmitate oxidized per gram of liver tissue per minute. ^#P < 0.05 for LC-treated mice versus LE-treated mice; *P < 0.05 for LE + Ad–treated mice versus LE-treated mice.