Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1–deficient mice
J. Clin. Invest. Shoshana Yakar, et al. 113:96 doi:10.1172/JCI17763 [Go to this article.]

Figure 2
LID mice expressing the GHa transgene exhibit enhanced insulin sensitivity. (a) Blood glucose levels were measured in the fed state in control, LID, GHa, and LID + GHa mice. (b) Serum insulin levels were measured in the fed state in the four genotypes. (c) Insulin tolerance tests were performed on the four genotypes of mice, as described in Methods. Results are expressed as the mean percentage of basal blood glucose concentration ± SEM. (*P < 0.05 compared with control; #P < 0.05 compared with GHa.)