Auricular chondritis in NOD.DQ8.Aβo (Ag7–/–) transgenic mice resembles human relapsing polychondritis
J. Clin. Invest. Veena Taneja, et al. 112:1843 doi:10.1172/JCI17450 [
Go to this article.]
Figure 4Sections from various organs of NOD.DQ8 mice stained with H&E. (
a) Representative inflammatory arthritis of the knee from a NOD.DQ8 mouse. Significant mononuclear infiltration with cartilage destruction and pannus formation is seen (*). (
b) Salivary glands showing mononuclear infiltrate suggestive of sialadentitis. (
c) Infiltration with mononuclear cells in the trachea. (
d) A section of lung shows perivascular infiltration in lungs. Accustain trichrome staining of frozen sections of trachea (
e) and lungs (
f). Only tracheas showed deposition of collagen, as seen by the blue color. Micrographs
a–
d are at ×100 magnification;
e and
f are at ×200 magnification.
