Auricular chondritis in NOD.DQ8.Aβo (Ag7–/–) transgenic mice resembles human relapsing polychondritis
J. Clin. Invest. Veena Taneja, et al. 112:1843 doi:10.1172/JCI17450 [
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Figure 2Characterization of the infiltrating cells in chondritic ear of NOD.DQ8 mice at 3 weeks and 8 weeks after onset of disease. At 3 weeks, CD4
+, B220
+, and Mac-1
+ cells were seen in abundance distributed throughout the section. Eight weeks after onset of chondritis, infiltrating CD4
+, CD8
+, and Mac-1
+ cells were reduced. B cells were present in aggregates, giving an appearance of follicles.