Auricular chondritis in NOD.DQ8.Aβo (Ag7–/–) transgenic mice resembles human relapsing polychondritis
J. Clin. Invest. Veena Taneja, et al. 112:1843 doi:10.1172/JCI17450 [
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Figure 1Swelling and edema with a shrunken ear as observed in a human ear (
a) and an affected mouse (
b) with auricular chondritis. H&E-stained section of a normal (
c) and a chondritic ear (
d) of NOD.DQ8 transgenic mice showing massive infiltration of cells in the chondritic ear. Toludine blue staining of a normal ear (
e) and a chondritic ear (
f) showing destruction of cartilage in the latter, with residual cartilage seen among infiltrates as shown within the boxed area (magnification ×200). Micrographs are ×50 magnification.