Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease
J. Clin. Invest. Vanda A. Lennon, et al. 111:907 doi:10.1172/JCI17429 [Go to this article.]

Figure 3
(a–c) Ocular signs of dysautonomia on day 28 after primary immunization. (a) Ptosis in an α3-GST responder rabbit (left), a sign of sympathetic denervation, was not observed in the adjuvant-inoculated control rabbit (right) or in seronegative rabbits. (b) In the same EAAN rabbit, lack of pupillary response to light is a sign of parasympathetic denervation. (c) Light stimulus induced prompt pupillary constriction in the control rabbit shown in a.