β-Arrestin-2 regulates the development of allergic asthma
J. Clin. Invest. Julia K.L. Walker, et al. 112:566 doi:10.1172/JCI17265 [Go to this article.]

Figure 5
IgG_2a production. (a) Total serum IgG_2a levels were not different between WT-OVA mice (black bars) and βarr2^–/–-OVA mice (white bars) at day 10, 17, or 24. Similarly, there was no difference in IgG_2a levels in serum from alum-treated WT (light gray bars) and alum-treated βarr2^–/– mice (dark gray bars). Data are mean ± SEM calculated from three independent experiments; n = 4–14 mice per group. (b) OVA-specific IgG_2a measurements were not different between WT-OVA mice (black bars) and βarr2^–/–-OVA mice (white bars) at day 24. Measurements were made using the endpoint titer method. Data are mean ± SD calculated from two experiments; n = 3 mice per group. ND, non-detectable.