Rheumatic fever–associated Streptococcus pyogenes isolates aggregate collagen
J. Clin. Invest. Katrin Dinkla, et al. 111:1905 doi:10.1172/JCI17247 [
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Figure 3Visualization of streptococcal capsule and binding of CIV gold complexes to M18 GAS. M18 strain 87282
S. pyogenes associated with ARF exhibit a thick capsule (
a), and loss of capsule after hyaluronidase treatment (
d). Low-voltage FESEM (1.5 kV) reveals binding of CIV gold complexes on M18 capsular structures (
b and
c), and highly reduced binding of CIV gold complexes on hyaluronidase-treated bacteria (
e). Bars, 1 μm (
a and
d), 0.5 μm (
b and
e), and 0.2 μm (
c).
