Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice
J. Clin. Invest. Masaya Kobayashi, et al. 111:1297 doi:10.1172/JCI17085 [Go to this article.]

Figure 4
IFN-γ production by CD4⁺ T cells in spleen and lamina propria of TNF-α/Stat3 double-mutant mice. CD4⁺ T cells were purified from spleen and lamina propria (LPL), and stimulated with plate-bound anti-CD3 Ab. The concentration of IFN-γ was measured by ELISA. CD4⁺ T cells from TNF-α/Stat3 double-mutant mice produced significantly increased levels of IFN-γ, similar to Stat3 mutant mice.