Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ
J. Clin. Invest. Robert S. Garofalo, et al. 112:197 doi:10.1172/JCI16885 [
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Figure 5Hyperglycemia and hyperinsulinemia in male and female Akt2-null mice. Plasma glucose (
a) and insulin (
b) levels were determined every 14 days in male wild-type (filled circles,
n = 11), male Akt2-null (open circles,
n = 12), female wild-type (filled diamonds,
n = 9), and female Akt2-null (open diamonds,
n = 13) mice.
