Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBβ
J. Clin. Invest. Robert S. Garofalo, et al. 112:197 doi:10.1172/JCI16885 [Go to this article.]

Figure 2
Adipose tissue mass is decreased in Akt2-null mice. Representative cross-sectional images of wild-type (WT) and Akt2-null (KO) male (a and b) and female (c and d) mice subjected to micro-CT analysis of in situ adipose tissue mass. (a and c) The inguinal subcutaneous (red) and epididymal/gonadal (green) depots and (b and d) the retroperitoneal (red) and mesenteric (green) depots are demarcated for illustration of the gross effect of the Akt2 deficiency on adipose tissue mass.