Regulation of pulmonary fibrosis by chemokine receptor CXCR3
J. Clin. Invest. Dianhua Jiang, et al. 114:291 doi:10.1172/JCI16861 [Go to this article.]

Figure 2
CXCR3^–/– mice exhibit a defect in lymphocyte and NK cell recruitment after lung injury. (A–D) After bleomycin treatment, BAL cells were collected on the indicated days and total cell (A) and differential cell counting (B–D) were performed (cells × 10⁵). Five mice were in each group at each time point. PMN, polymorphonuclear leukocytes. **P < 0.05. (E) FACS analysis of BAL cells using specific Ab’s to CD3, CD8, CD4, and the NK cell marker, NK1.1. Percentages of CD3⁺, CD8⁺, CD4⁺, and NK1.1⁺ cells were plotted. Five animals in each group were tested. *P < 0.01, **P < 0.05.