A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I
J. Clin. Invest. Nan Wang, et al. 111:99 doi:10.1172/JCI16808 [Go to this article.]

Figure 3
Calpeptin increases ABCA1 in primary mouse macrophages and hepatocytes. Levels of ABCA1 in mouse peritoneal macrophages (a) or primary mouse hepatocytes (b) incubated with or without calpeptin at indicated concentration for 3 hours. The data are representative of three independent experiments with similar results.