Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis
J. Clin. Invest. Despina Moshous, et al. 111:381 doi:10.1172/JCI16774 [Go to this article.]

Figure 5
Complementation of IR sensitivity. (a) Fibroblasts from P70 were complemented with WT Artemis. The selective advantage of transduced cells after 3 Gy IR was assessed over time. The control curves, (vector 0 Gy) and (vector 3 Gy), are superimposed. (b) Fibroblasts from an Artemis-deficient patient were complemented with either the WT or the P70-specific truncated form of Artemis. The selective advantage of transduced cells after 4 Gy IR was assessed over time. Results are expressed as the GFP⁺/GFP^– cell ratio over time following irradiation.