Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis
J. Clin. Invest. Despina Moshous, et al. 111:381 doi:10.1172/JCI16774 [
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Figure 4TCR-β junction analysis. (
a) TCR CDR3-length profile of Vβ2, Vβ5, and Vβ6 cell populations in lymphocytes from P69 and P70 (solid lines) and control (dashed lines). Determination was performed by the Immunoscope method. The relative intensity of the bands (
y axis) was plotted as a function of CDR3 size. (
b) Sequence of TCR-β V(D)J junctions for Vβ2 in lymphocytes from P69, P70, and control. P nucleotides are represented in is.