Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy
J. Clin. Invest. Hiroaki Yagyu, et al. 111:419 doi:10.1172/JCI16751 [
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Figure 7Two-dimensional echocardiogram. Representative echocardiographic images from
LpL1 (
a and
b) and hLpL
GPI/
LpL1 (
c and
d) mice at end-diastole (left;
a and
c) and end-systole (right;
b and
d). The left ventricles of hLpL
GPI/
LpL1 6-month-old female mice were significantly larger than control
LpL1 mice (see Table
1).