Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo
J. Clin. Invest. Matthijs K.C. Hesselink, et al. 111:479 doi:10.1172/JCI16653 [
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Figure 1(
a) Representative Western blot of human lung (
1), human liver (
2), human white adipose tissue (
3), and two human vastus lateralis muscle samples (4 and 5) after loading similar amounts of protein. (
b) Western blot of medial gastrocnemius muscle from a transgenic mouse overexpressing human UCP3 (
1) and a wild-type littermate (
2). Note the lack of cross-reactivity in tissues known to express UCP2 but not UCP3 (
a) and the lack of cross-reactivity with endogenous mouse UCP3 (
b).