The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse
J. Clin. Invest. Gregory B. Lesinski, et al. 112:170 doi:10.1172/JCI16603 [
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Figure 3Survival of mice bearing the STAT1-deficient AGS-1 murine melanoma cell line. IFN-α treatment (open triangles) prolonged the survival of C57BL/6 mice (
n = 6 mice per group) challenged with the STAT1-deficient AGS-1 melanoma cell line as compared with PBS-treated mice (filled circles) (
P = 0.008). These results are representative of two separate determinations.
