The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse
J. Clin. Invest. Gregory B. Lesinski, et al. 112:170 doi:10.1172/JCI16603 [Go to this article.]

Figure 2
Antiproliferative effects of IFN-α in murine melanoma cell lines. Proliferation of the B16F1 and AGS-1 cell lines was measured by the MTT assay. IFN-α inhibits proliferation of B16F1 melanoma cells in a dose-dependent manner. In contrast, the antiproliferative effects of IFN-α were absent in the AGS-1 cell line at all concentrations tested. Results represent the mean of triplicate wells and are expressed as optical density at 570 nm ± SE.