A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia
J. Clin. Invest. Shigeki Katoh, et al. 111:1563 doi:10.1172/JCI16583 [Go to this article.]

Figure 8
Anti-CD44 mAb inhibits mite allergen–induced airway inflammation and airway hyperreactivity. The number of inflammatory cells in BALF (a) and airway responsiveness to aerosol methacholine (b) was determined 24 h after mite allergen challenge as described in Methods. Data represent mean ± SEM. The values shown are averaged from five independent experiments. ^#Significant differences (P < 0.05) between mite allergen–challenged (Der) RIgG-treatment mice (Der/RIgG) and PBS-challenged mice (PBS). *Significant differences (P < 0.05) between Der-challenged anti-CD44 mAb-treatment mice (Der/IM7) and Der-challenged RIgG-treatment mice (Der/RIgG).