A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia
J. Clin. Invest. Shigeki Katoh, et al. 111:1563 doi:10.1172/JCI16583 [Go to this article.]

Figure 1
Anti-CD44 mAb blocks eosinophil and lymphocyte accumulation in BALF but does not affect numbers of eosinophils in bone marrow. The number of inflammatory cells in BALF (a) and percentages of eosinophils in bone marrow and peripheral blood (b) was determined 24 h after allergen challenge as described in Methods. Data represent mean ± SEM. The values shown are averaged from three to five independent experiments. ^#Significant differences (P < 0.05) between Asc-challenged mice (Asc) and PBS-challenged mice (PBS). *Significant differences (P < 0.05) between Asc-challenged anti-CD44 mAb-treatment mice (Asc/KM201, Asc/IM7, or Asc/IM7/30) and Asc-challenged RIgG-treatment mice (Asc/RIgG).