Cancer-associated immunodeficiency and dendritic cell abnormalities mediated by the prostaglandin EP2 receptor
J. Clin. Invest. Li Yang, et al. 111:727 doi:10.1172/JCI16492 [Go to this article.]

Figure 3
OVA MLR T cell proliferation in wild-type and EP2-null cells. DCs were pulsed with the indicated quantity of OVA 323–339 and used to stimulate T cells bearing the OVA-specific TCR (DO11.10). Proliferation of T cells was measured by ³[H] thymidine uptake. Wild-type T cells are represented by filled symbols, EP2 heterozygotes by shaded symbols, and EP2-null T cells by open symbols. The data are the mean ± SEM of triplicate measurements. *EP2-null value was significantly different from wild-type value (P < 0.01). **EP2-null value is significantly different from wild-type value (P < 0.001).