Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma
J. Clin. Invest. Yong-Geun Kwak, et al. 111:1083 doi:10.1172/JCI16440 [Go to this article.]

Figure 5
Localization of immunoreactive PTEN in lung tissues and tracheal epithelial cells of OVA-sensitized and -challenged mice. Sampling was performed 72 hours after the last challenge in lung tissues and tracheal epithelial cells from sensitized mice challenged with saline (a and e), from sensitized mice challenged with OVA (b and f), from OVA-inhaled mice administered AdPTEN (c), and from OVA-inhaled mice administered AdLacZ (d). Representative light microscopy shows PTEN-positive cells in the bronchioles (a, b, c, and d; the brown color indicates PTEN-positive cells) and in the tracheal epithelial cells (e and f; the dark brown color indicates PTEN-positive cells). Bars indicate scale of 50 μm (a, b, c, and d) or 10 μm (e and f).