Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma
J. Clin. Invest. Yong-Geun Kwak, et al. 111:1083 doi:10.1172/JCI16440 [Go to this article.]

Figure 2
Inducible PI3K enzyme activity in lung tissues of OVA-sensitized and -challenged mice. (a) PI3K activity was measured in lung tissues from sensitized mice challenged with OVA (upper panel) or with saline (lower panel). (b) Results of densitometric analysis are presented as the relative ratio of induction of PI3K before and after the challenge. The PI3K activity in the lung tissue of preinhalation mice is arbitrarily presented as 1. Data represent mean ± SD from six independent experiments. Pre, before challenge; 1, 24, 48, and 72 hours are time periods after the last challenge. *P < 0.05 vs. Pre; ^#P < 0.05 vs. saline inhalation.