Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease
J. Clin. Invest. Erik S. Barton, et al. 111:1823 doi:10.1172/JCI16303 [
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Figure 2Growth of T3SA– and T3SA+ in mice after intracranial inoculation. ND4 Swiss Webster mice, 2–3 days old, were inoculated intracranially with 1 × 10
3 PFU of either T3SA– or T3SA+ in a volume of 5 μl. At the indicated times after inoculation, mice were euthanized and brains were collected. Brain tissue was homogenized by sonication, and titers of virus present in homogenates were determined by plaque assay. Each data point represents the average viral titer from two to four brains.
