FTY720 stimulates multidrug transporter– and cysteinyl leukotriene–dependent T cell chemotaxis to lymph nodes
J. Clin. Invest. Shaun M. Honig, et al. 111:627 doi:10.1172/JCI16200 [
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Figure 1FTY720 enhances efflux activity of the Abcb1 and Abcc1 transporters. (
a–
d) Abcb1 efflux activity (
a and
c) and Abcc1 efflux activity (
b and
d) in wild-type C57BL/6 T cells. (
e and
f) Abcb1 (
e) and Abcc1 (
f) efflux activity in
Abcc1–/– T cells. (
g and
h) Abcb1 (
g) and Abcc1 (
h) efflux activity in
Abcb1–/– T cells.
