Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo
J. Clin. Invest. Weijun Jin, et al. 111:357 doi:10.1172/JCI16146 [
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Figure 2Plasma lipoprotein profiles at baseline and after antibody injection. Pooled plasma samples obtained at baseline and 48 hours after control or anti-mEL IgG injection were subjected to FPLC using Superose 6 columns, and the cholesterol concentration in each fraction was measured. (
a) Wild-type mice. (
b)
HL–/– mice. (
c) Human apoA-I transgenic mice.