The α_1A/C- and α_1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse
J. Clin. Invest. Timothy D. O’Connell, et al. 111:1783 doi:10.1172/JCI16100 [Go to this article.]

Figure 2
Heart growth in male ABKO and WT mice. (a) Typical hearts at 12 weeks. Twelve-week-old male mice had the wet HWs and BWs shown. (b) HW versus age. Wet HW in male mice from weaning (3 weeks) to young adulthood (14 weeks) is plotted versus age. Curves were fit using nonlinear regression (F = 17.81, P < 0.005). Heart growth after weaning in the ABKO mice was only 60% of that in WT; BW was the same as in WT (not shown).