The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse
J. Clin. Invest. Timothy D. O’Connell, et al. 111:1783 doi:10.1172/JCI16100 [
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Figure 1α
1-AR subtype mRNA levels and receptor binding in hearts from ABKO and WT mice. (
a) α
1-AR subtype mRNAs by RPA. RNA was from ventricles of 10-week-old male mice. (
b) α
1-AR saturation binding. [3H]-prazosin was used with ventricular membranes from 10-week-old male and female mice;
n = 4 of each sex and genotype.