Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes
J. Clin. Invest. Raymond J. Steptoe, et al. 111:1357 doi:10.1172/JCI15995 [Go to this article.]

Figure 5
T cell recall responses to OVA immunization. Mice were immunized subcutaneously with OVA 10 weeks after BMT, and recall responses of splenic T cells were measured 14 days later. T cell proliferation in the presence of OVA was similar in recipients of T cell–depleted NOD (inverted triangles) or NOD-PI (triangles) BM and in age-matched control NOD mice (squares). Data are from individual mice pooled from three separate experiments in which BMT from NOD and NOD-PI was performed in parallel.