Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
J. Clin. Invest. Jean-Pierre Lévesque, et al. 111:187 doi:10.1172/JCI15994 [Go to this article.]

Figure 2
BM loses reactivity for anti-human CXCR4 mAb 6H8 during mobilization with GCSF. BM sections taken before mobilization were stained with a nonimmune IgG1 (a) and mAb 6H8 (b and c). Positive staining appears in purple (magnification, ×400). 6H8 staining on BM on day 4 of GCSF administration was very dim (c). The scale bar represents 50 μm.