Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase–deficient mouse adipose tissue
J. Clin. Invest. Dagmar Kratky, et al. 115:161 doi:10.1172/JCI15972 [Go to this article.]

Figure 5
Uptake and incorporation of PL-derived FFAs by AT. Fat pads of mice in the presence (L2) or absence (L0-MCK) of LPL were incubated with DMEM/10% lipoprotein-deficient serum (LPDS) containing [¹⁴C]PC-labeled HDL (50 μg HDL-associated protein/sample) at 37°C for 6 hours. The incorporation of FFAs into the TG moiety of AT was performed in the absence (control) or presence of 50 μg anti-EL IgG, 50 μg/ml THL or/and 2 U/ml heparin in a total volume of 150 μl. Results are mean ± SD from 5 mice of each genotype performed in duplicate. **P – 0.01.