Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T
J. Clin. Invest. Maryam M. Javadpour, et al. 112:768 doi:10.1172/JCI15967 [Go to this article.]

Figure 2
Plot of the relationship between RPP and |ΔG_∼ATP| for NTG (squares, n = 9), WT-Tg (triangles, n = 4), and R92Q (circles, n = 8) hearts perfused with buffers containing glucose and pyruvate with 2.5 mM (open symbols) and 4.0 mM (filled symbols) Ca²⁺. The means of the NTG hearts (large squares), WT-Tg hearts (large triangles), and R92Q hearts (large circles) for each workload are connected. The relationships for NTG and WT-Tg mice are indistinguishable; the relationship for R92Q hearts differs from that of both NTG and WT-Tg hearts.