Obesity resistance and enhanced glucose metabolismin mice transplanted with white adipose tissue lackingacyl CoA:diacylglycerol acyltransferase 1
J. Clin. Invest. Hubert C. Chen, et al. 111:1715 doi:10.1172/JCI15859 [
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Figure 7Expression of adipocyte-derived molecules. (
a) Resistin, TNF-α, and adiponectin expression in WAT of
Dgat1–/– mice.
n = 7–10 male mice per group. Error bars represent SEM. *
P < 0.05 vs.
Dgat1+/+ mice fed a high-fat diet for 20 weeks. (
b) Comparison of adiponectin expression in transplanted
AY/a Dgat1–/– WAT and native
AY/a Dgat1+/+ WAT obtained from transplanted mice.
n = 4 male mice per group. *
P <0.05 vs. naive WAT. (
c) Effect of leptin infusion on adiponectin expression in
ob/ob Dgat1–/– mice.
n = 3–5 male mice per group. Expression of chow-fed
Dgat1+/+ mice = 1.0. *
P < 0.05 vs.
ob/ob Dgat1+/+ mice without leptin treatment. (
d) Effect of leptin infusion on adiponectin expression in
Dgat1–/– and
Dgat1+/+ mice.
n = 8–10 male mice per group.