Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis
J. Clin. Invest. Wanhong Ding, et al. 111:1923 doi:10.1172/JCI15722 [
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Figure 8Splenocytes from vIL-10Tg mice demonstrate enhanced NK cell activity compared with splenocytes from WT mice. Varying numbers of splenocytes (effector cells) from vIL-10Tg and WT mice were incubated with YAC-1 cells (target cells) for 4 hours in round-bottomed 96-well plates. Cells from vIL-10Tg mice exhibited significantly greater NK cell activity than cells from WT mice (
P = 0.01).