Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis
J. Clin. Invest. Wanhong Ding, et al. 111:1923 doi:10.1172/JCI15722 [
Go to this article.]
Figure 7vIL-10Tg mice develop fewer skin tumors in response to chronic UVB irradiation. Groups of WT and vIL-10Tg mice were exposed to 2.16 kJ/m
2 of UVB irradiation from FS40 sunlamps three times per week for 27 weeks. Significantly fewer tumors developed over time in vIL-10Tg mice than in WT control mice (
P < 0.05;
n = 20, both groups).
