Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis
J. Clin. Invest. Wanhong Ding, et al. 111:1923 doi:10.1172/JCI15722 [Go to this article.]

Figure 4
Cultured ECs from vIL-10Tg mice have decreased expression of CD80 and CD86. Fresh ECs were prepared from both vIL-10Tg and WT mice, cultured for 72 hours in vitro, and then stained with PE-labeled anti-CD80 or anti-CD86. The mean fluorescence intensity of CD80 (a) and CD86 (b) was assessed. n = 5. (a) P = 0.0008, vIL-10Tg vs. WT. (b) P = 0.03, vIL-10Tg vs. WT.