Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis
J. Clin. Invest. Wanhong Ding, et al. 111:1923 doi:10.1172/JCI15722 [Go to this article.]

Figure 1
ECs from vIL-10Tg mice express mRNA for vIL-10 and secrete vIL-10 protein. (a) RT-PCR. Lane 1, DNA standard; lane 2, WT mice; lane 3, heterozygote transgenic mouse; lanes 4–8, homozygote transgenic mice; lane 9, RNA/PCR without RT. (b) vIL-10 in supernatants from fresh EC cultures and serum was measured by ELISA. (c) vIL-10 could be detected in serum from vIL-10Tg mice. n = 5, both groups. Error bars represent ± SE. (b) P < 0.0005, vIL-10Tg vs. WT; (c) P = 0.0005, vIL-10Tg vs. WT.