Increased plasma phenylacetic acid in patients with end-stage renal failure inhibits iNOS expression
J. Clin. Invest. J. Jankowski, et al. 112:256 doi:10.1172/JCI15524 [
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Figure 2Cell viability of RAW 264.7 cells in the presence of PAA. Cell viability was assessed using Trypan blue dye. RAW 264.7 cells were stimulated (stim) or not (control) for 12 hours with LPS (1 μg/ml). Viability of cells was measured after stimulation with LPS and in the presence of various concentrations of PAA (0.1 mmol/l, 0.5 mmol/l, 1.0 mmol/l, and 5.0 mmol/l). Data are mean ± SEM (
n = 6).
P < 0.05 compared with stimulated cells.
