Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings
J. Clin. Invest. Taizo Wada, et al. 111:1389 doi:10.1172/JCI15485 [
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Figure 2Flow-cytometric analysis of WASP. PBMCs were stained with mAbs for cell-surface antigens, fixed, and permeabilized. Cells were then reacted with anti-WASP mAb (gray histogram) or a control Ab (white histogram) and further incubated with biotin-conjugated anti-mouse IgG-1 followed by streptavidin-PE. Shown are the results of WASP expression in leukocytes from a healthy control and patients II-1 and II-2.