Renal protection from ischemia mediated by A_2A adenosine receptors on bone marrow–derived cells
J. Clin. Invest. Yuan-Ji Day, et al. 112:883 doi:10.1172/JCI15483 [Go to this article.]

Figure 3
Immunohistochemistry of GFP-positive cells in kidney of GFP mice and GFP→WT chimera. (a) Immunohistochemical localization of GFP in outer medulla of kidney from GFP mice. Magnification, ×630. Endothelial cells are identified by arrows. (b) Outer medulla of kidney from GFP→WT chimeras after renal IRI. Donor BM-derived cells are identified by arrows. Magnification, ×630. (c and d) Dual labeling of kidney from GFP→WT chimeras after renal IRI. Labeling with anti-GFP antibody (c) reveals cells of donor origin (arrows, c) that are identified as macrophages (arrows, d) by labeling with anti-macrophage antibody (d). Arrowhead indicates recipient macrophage. Magnification, ×1000 in (c) through (d).