β2 integrins are required for skin homing of primed T cells but not for priming naive T cells
J. Clin. Invest. Stephan Grabbe, et al. 109:183 doi:10.1172/JCI11703 [
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Figure 5Irritant dermatitis in
CD18–/– mice. Irritant dermatitis was elicited by application of 10 μl 0.8% croton oil to both sides of one ear, and measurement of ear swelling responses (
a) and histological examination (
b) were performed 18 hours later. Arrows indicate dilated blood vessels with endothelium-associated leukocytes, some of which appear to have extravasated. Original magnification, ×200. *
P = not significant.