β₂ integrins are required for skin homing of primed T cells but not for priming naive T cells
J. Clin. Invest. Stephan Grabbe, et al. 109:183 doi:10.1172/JCI11703 [Go to this article.]

Figure 2
ACD and irritant dermatitis to epicutaneous application of OXA in CD18^–/– mice. Mice were sensitized to OXA by epicutaneous application of various concentrations of OXA as described in Methods. Six days later, mice were OXA-challenged at one ear to induce ACD, and ear swelling was determined 30 hours later. (a) ACD, titration of sensitization dose. (b) ACD, titration of challenge dose. (c) Irritant dermatitis to epicutaneous application of OXA.