Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation
J. Clin. Invest. Mai-Lan N. Huynh, et al. 109:41 doi:10.1172/JCI11638 [
Go to this article.]

Figure 5In vivo TGF-β1 induction by PLB-985 cells. Viable PLB or apoptotic PLB cells (ApoPLB) and apoptotic Jurkat T cells (ApoJ) were injected into thioglycollate-stimulated peritonea. In the lavage fluid and cells obtained 1 hour later, (
a) phagocytic indexes were comparable in the ApoPLB and ApoJ groups. (
b) Viable PLB and ApoPLB cells failed to induce TGF-β1, in comparison with ApoJ. *
P < 0.02,
n ≥ 10, ± SD.